Bio-Data

Particulars of organization, functions and duties

Dr. P Yuvaraj

Designation : Principal Scientist

Education : Ph D (Organic Chemistry)

Contact Details: Ph: +91 0385-2414481 / Fax +91 0385-2414481

Email id : yuvaraj.orgchem@gmail.com, pyuvraj@neist.res.in

Research Interest

• Diastereoselective synthesis of Lamellarin alkaloid natural product fused spirooxindoles and its analogues. A series of evaluation of its biological activities against Mycobacterium tuberculosis and other bacteria. DST-SERB India. Principal Investigator
• Synthesis of analogues of natural products having anticancer potential and investigation on their chemico-therapeutic potential to mitigate lung cancer. DBT-RA, Principal Investigator
• Design and synthesis of polycyclic heteroarenes using Rh(III), Ru(II) or Co(III) catalyzed C- H activation/annulation and their live cell imaging applications.SERB-N-PDF. Principal Investigator

• CSIR-Aroma Mission I & II
• CSIR- Phytopharmaceuticals Mission
• CSIR- Floriculture Mission

• Prospecting of local bioresources of northeast India with special reference to (MLP 8000).
• Sustainable utilization of available flora of Manipur & Arunachal Pradesh for the benefit to society (OLP-2006).
• Bio-prospection and therapeutic evaluation of selected medicinal, aromatic, and economic plants (MAP) in Arunachal & Manipur (OLP-2016).
• Bio-prospection and value-added products from medicinal, aromatic, and economic plant (MAP) (OLP-2024).
• Augmentation of bioresources for environmental care andsocio-economic development (OLP-2043).
• Bio-prospecting underutilized plants for socio-economic development (OLP-2067)

• Transition Metal‐Free Synthesis of N‐Heterocyclic Compounds via Multicomponent Reaction. Dhruba Jyoti Boruah, Lodsna Borkotoky, Uma Devi Newar, Ram Awatar Maurya, P. Yuvaraj. Asian Journal of Organic Chemistry, e202300297. 2023
• Design and synthesis of photostable triphenylamine based neutral AIE nano luminogens: specific and long-term tracking of mitochondria in cells.Kathirvelan Devarajan, Mayakrishnan Sivakalai, Suparna Mercy Basu, Chinmoy Biswas, Meenakshi Chauhan, Uzma Hasan, P. Yuvaraj, Uma Maheswari Narayanan, Sai Santosh Kumar Raavi, Jyotsnendu Giri, Tarun K Panda. Biomaterials Science. 11 (11), 3938-3951. 2023
• Catalyst-Free, Room-Temperature Accessible Regioselective Synthesis of Spiroquinolines and Their Antioxidant Study.Paras J Patel, Divyang M Patel, Ruturajsinh M Vala, Subham G Patel, Dipti B Upadhyay, P. Yuvaraj Hitendra M Patel. ACS omega8 (1), 444-456. 2023
• Design and synthesis of spirooxindole–pyrrolidines embedded with indole and pyridine heterocycles by multicomponent reaction: anticancer and in silico studies. Sivakalai Mayakrishnan, Devarajan Kathirvelan, Yuvaraj Arun, Krishnan Saranraj, Chandrasekaran Balachandran, Shin Aoki, P.Yuvaraj, Narayanan Uma Maheswarai. New J. Chem., 2022, 46, 10089-10106.
• Design, synthesis via a one-pot approach and molecular docking studies of novel pyrrolo [2, 1-a] isoquinoline derivatives. Dhruba Jyoti Boruah, Devarajan Kathirvelan, Satheesh Borra, Ram Awatar Maurya, P. Yuvaraj.  New J. Chem., 2022, 46, 792-797.
• An Efficient Synthesis of Heterogeneous and Hard Bound TiIV‐MCM‐41 Catalyzed Mannich Bases and π‐Conjugated Imines. Shenbagapushpam Muthumanickam, Muthukumar Thennila, P. Yuvaraj, Kanthapalam Arun Prasath Lingam, Kodirajan Selvakumar. ChemistrySelect, 2021, 6, 14071-14076.
• Highly efficient endo'- selective synthesis of (dispiro 3,2’-pyrrolidinyl) bisoxindoles containing three contiguous chiral stereocenters with two contiguous quaternary spirostereocenters. P. Yuvaraj, Huidrom Birkumar Singh, Kandapalam Arun Prasath Lingam, Devarajan Kathirvelan and Sankaranarayanan Nagarajan. Springer- J. Chem. Sci.132, 76, 2020.
• Chemo-selective synthesis of [indoline-3,4'-isoxazolo[5,4-b]pyridine fused spirooxindole derivatives via brønsted acid catalysed three–component. Dhruba Jyoti  Boruah ,                  P. Yuvaraj ,   Ram Awatar  Maurya . Results in Chemistry 2, 2020, 100064.
• Heterogeneous Cu(I)-SBA-15 Mediated Catalytic Reduction of Substituted NitroarenesMuthukumar Thennila, Shenbagapushpam Muthumanickam, Dr. Madasamy Sivabharathy, P. Yuvaraj, Dr. Kodirajan Selvakumar. ChemistrySelect, 2020, 5, 11843– 11849.
• Controlled and Efficient Stereoselective Synthesis of Oxindole Appended 1-Aza-1,3-Butadiene Derivatives via One Pot Buchwald-Hartwig Amination/ Elimination Strategy.  K. A. P. Lingam, P. Amutha, P.  Yuvaraj, K. Selvakumar. Synthesis. 2017, 49, A-H.

• Qualified GATE (Graduate Aptitude Test in Engineering) exam in 2010.
• CSIR- Senior Research Fellowship (SRF) from the Council of Scientific and Industrial Research (2012 – 2015).
• Postdoctoral Fellow, University of KwaZulu Natal, South Africa (Feb-2015-Nov-2015).
• Postdoctoral Fellow, IIT Madras, Chennai, India. (Dec-2015-Mar-2016).
• Shortlisted for the CSIR Young Scientist Award 2019 in Chemical Sciences.

• Mr. Dhruba Jyoti Boruah, AcSIR Ph.D. student
• Dr. Khumukcham Nongalleima, DBT-RA
• Dr. S. Mayakrishnan. SERB-NPDF