R&D PROGRAMS

Ongoing R & D Programme:

• 1.MLP 2000: Bio-profiling and bio-prospecting microbes, plants and insects from North East gene pool and their application potentials.
• 2.GPP 0290: Isolation and characterization of antifungal peptides from muga silkworm Antheraea assamensis Helfer.
• 3.GPP 0271: Detoxification of mustard seed based product through fermentation process based on North east traditional practices and their value addition.
• 4. BSC 0105: New initiative to boost agriculture productivity through maximizing pre and post harvest yields (Agropathy).
• 5. CSC 0106 : Biocatalyst for industrial application and greener organic synthesis (BIAGOS)
• 6.CSC0116 : Photobiological process to produce bioenergy through carbon sequestration from atmosphere and wastewater.
• 7. CSC 0131: Environmental Research Initiative for Paper and Process Industry (ERIPP) Sub Title: Clean Technology for Pulp Processing.
• 8. GPP 0291: DNA fingerprinting of Lignocellulose degrading microbes isolated from protected forest areas of Assam and Mizoram.
• 9. BSC 0109: Studying adaptation biology and understanding/exploiting medicinally important plants for useful bioactive (SIMPLE)
• 10. BSC 0116: Therapeutics of Chronic obstructive pulmonary diseases (COPD) and related respiratory disorder (TREAT).
• 11. GPP 0260: Screening and molecular characterization of microbial pathogen diversity of Staphylococci and development of diagnostic test for rapid detection.
• 12.BSC 0111: Integrated NextGen Approaches in Health, Disease and Environmental Toxicity (INDEPTH).
• 13. GAP 0733 : Investigate the molecular mechanism by which micronutrient supplementation improves glycemic status and reduces vascular inflammation in type 2 diabetes.
• 14.GAP 0732 : Role of SAM Pointed Domain Containing ETS Transcription Factor (SPDEF) in distinguishing indolent from aggressive prostate cancer and in the improvement of resistance to conventional therapy of prostate cancer.
• 15. BSC 0116 : Therapeutics of Chronic obstructive pulmonary diseases (COPD) and related respiratory disorder (TREAT).
• 16. GPP 0260 : Screening and molecular characterization of microbial pathogen diversity of Staphylococci and development of diagnostic test for rapid detection.
• 17.GAP 0733 : Investigate the molecular mechanism by which micronutrient supplementation improves glycemic status and reduces vascular inflammation in type 2 diabetes.
• 18. GAP 0732 : Role of SAM Pointed Domain Containing ETS Transcription Factor (SPDEF) in distinguishing indolent from aggressive prostate cancer and in the improvement of resistance to conventional therapy of prostate cancer.
• 19. GPP 0292: Mining the metagenome for bacterial diversity in extreme areas of NE India under (ICAR- AMAAS-Project).
• 20. BSC 0117: Role of ACC-deaminase producing PGPR on alleviation of water stress affect on pulse crops (RAWS, under PMSI).
• 21. SERB-RJN078/2014: Role of DEAD-Box RNA helicases in regulating multiple abiotic stress responses in model plant Arabidopsis thaliana.
• 22. Testing facilities (water & soil).
• 23. GPP-0200: Bioinformatics Infrastructure Facility (BIF Centre).
• 24. GPP-0246: Institutional Biotechnology Hub.
• 25. CLP0286: Development of commercial bioformulation of Plant Growth Promoting Rhizobacteria (PGPR) using Coir pith as carrier.

Acheivements

• Isolated >700 strains from specific niches of Northeast India & screened for different biological properties like stress tolerance, IAA, ACC-deaminase, lipase, xylanase, cellulase, laccase etc.
• Bioremediation of Crude oil contaminated land.
• Few PGPR strains evaluated for nematode control in plant.
• Isolated various strains having broad spectrum antimicrobial activity against Gram positive and Gram negative bacteria.
• Full genome sequencing and complete analysis- Pseudomonas aeruginosa N002 (Crude oil degrading bacteria), Micromonospora sp. HK10 strain (Antibacterial compound producing Actinobacteria) and Streptomyces sp. RSD27 (isolated from Tawang).
• Isolation, purification and bioassay of Staphylocoagulase against human blood
• Isolation & characterization of antifungal peptides from muga silkworm Antheraea assamensis Helfer
• Antimicrobial biosynthetic potential and genetic diversity of endophytic actinomycetes associated with medicinal plants.
• Community profiling of culturable fluorescent pseudomonads in the rhizosphere of green gram.
• Bacterial community profiling in different environmental niches of North-East India.
• through Next-Generation Sequencing (Illumina MiSeq) approach.
• Development of Plant based formulation for Control of Insect pest of Stored Pulses & Cereals.
• Penicillium citrinum MTCC12422, fungal isolate, biotransformed artimisinin to deoxyartimisinin.
• Methods for biomass production from screened microalgae were optimized.
• Role of environmental pollutants in liver physiology: Special references to peoples living in the oil drilling sites of Assam
• Six forest habitat: classification, diversity, soil and aboveground biomass were determined.
• Studies with bacterial consortium (PGPR) as an enhancer for vegetable crops. The field experiments that were laid to see the potency of three bacterial strains having PGPR properties were found to be effective in increasing height, no. of leaves and biomass as compared to the control crops.

Research Facilities

1. PCR
2. HPLC
3. Shaker
4. RT-PCR
5. Ice maker
6. Incubator
7. Fume hood
8. Laminar Hood
9. Lyophilizer
10. Cold room
11. Bioreactor
12. Water bath
13. Electroporator
14. Orbital Shaker
15. -20°C freezer
16. 4°C Refrigerator
17. -80°C Ultra freezer
18. Biosafety Cabinet
19. Micro plate reader
20. Micro plate reader
21. Cell Culture Facilities
22. UV-Spectrophotometer
23. Fluorescent Microscopy
24. Milli Q- water purification system
25. Molecular Imager Gel doc system
26. DNA & Protein gel running apparatus
27. Table top and refrigerated micro Centrifuge
28. Plant Cell and Tissue Culture Facility