Bio-Data

Particulars of organization, functions and duties

Dr. Rinku Baishya

Designation : Sr. Scientist

Education : M.S. (Pharm.), NIPER Kolkata, Ph.D. (Pharmaceutical Sciences), CSIR-IICB, Kolkata, Post Doctoral Fellow, Ben Gurion University, Israel

Contact Details: Chemical Science &Technology Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam-785006, Ph- 9874492416, Fax: 0376-2370011

Email id : rbaishya@neist.res.in, rinku.niper@gmail.com
Personal Website

Research Interest

• Screening of Natural and Synthetic compounds for anti-inflammatory and anticancer potential
• To explore and validate the traditional medicines as well as foods of Northeast India through pioneering scientific screening and research in pharmacology to develop an effective, safe and reliable health products.
• Formulation of herbal drugs and evaluate its safety, efficacy and preparation of dosage form
• Studying application and development of effective long-term delivery systems for anti-cancer drugs, growth factors, gene therapy agents, vaccines, etc.
• In vivo pharmacokinetic analysis and bioavailability.
• Nanoparticle formulation and in vitro biological studies, fluorescent labeling, blood clearance.

• Roy E, Mridha P, Baishya R, Bora HK, Konwar R, Das MR. Carbon Nanotropes: Potential Nanomaterials for Drug Delivery and Biomedical Applications. InCarbon Nanostructures in Biomedical Applications 2023 May 5 (pp. 197-227). Cham: Springer International Publishing.
• Das DJ, Boruah JL, Famhawite V, Puro N, Bora PK, Gogoi M, Biswas A, Yadav A, Haldar S, Baishya R. Antibacterial potential of an ethnic probiotic containing food, Akhuni/Axone and its chemical characterization. Food Chemistry Advances. 2023 Oct 1;2:100221.
• Darshani P, SenSarma S, Srivastava AK, Baishya R, Kumar D. Anti-viral triterpenes: a review. Phytochemistry Reviews. 2022 Dec;21(6):1761-842.
• Sarmah M, Das DJ, Dutta D, Baishya R, Gogoi P. A Versatile Pd-Catalyzed Alkyne Annulation Process for Benzo [a] carbazoles and their Anticancer Analogues. ACS Omega. 2022 Nov 29;7(51):47680-700.
• Sahu BP, Baishya R, Hatiboruah JL, Laloo D, Biswas N. A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches. Journal of Pharmaceutical Investigation. 2022 Sep;52(5):539-85.
• Gogoi M, Boruah JL, Bora PK, Das DJ, Famhawite V, Biswas A, Puro N, Kalita J, Haldar S, Baishya R. Citrus macroptera induces apoptosis via death receptor and mitochondrial mediated pathway as prooxidant in human non-small cell lung cancer cells. Food Bioscience. 2021 Oct 1;43:101293.
• Yatham P, Dahat Y, Khan A, Baishya R, Srivastava AK, Kumar D. Saponin stabilized emulsion as sustainable drug delivery system: Current status and future prospects. Nanopharmaceutical Advanced Delivery Systems. 2021 Jan 12:217-35.
• Baishya R, HatiBoruah JL, Bordoloi MJ, Kumar D, Kalita P. Novel drug delivery system in phytochemicals: modern era of ancient science. Herbal Medicine in India: Indigenous Knowledge, Practice, Innovation and its Value. 2020:175-89.
• Gaonkar RH, Baishya R, Paul B, Dewanjee S, Ganguly S, Debnath MC, Ganguly S. Development of a peptide-based bifunctionalchelator conjugated to a cytotoxic drug for the treatment of melanotic melanoma. MedChemComm. 2018;9(5):812-26.
• Baishya R, Nayak DK, Kumar D, Sinha S, Gupta A, Ganguly S, Debnath MC. Ursolic acid loaded PLGA nanoparticles : in vitro and in vivo evaluation to explore tumor targeting ability on B16F10 melanoma cell lines. Pharm Res. 2016 Nov;33(11):2691-703.
• Sahu BP, Hazarika H, Bharadwaj R, Loying P, Baishya R, Dash S, Das MK. Curcumin-docetaxel co-loaded nanosuspension for enhanced anti-breast cancer activity. Expert Opin Drug Deliv. 2016 Aug;13(8):1065-74.
• Gaonkar RH, Ganguly S, Baishya R, Dewanjee S, Sinha S, Gupta A, Ganguly S, Debnath MC. Exploring the Potential of 99mTc(CO)3-labeled triazolyl peptides for tumor diagnosis. Cancer BiotherRadiopharm. 2016 Apr;31(3):110-7.
• SatapathyBS, MukherjeeB, BaishyaR, DebnathMC, DeyNS, MajiR. Lipid nanocarrier-based transport of docetaxel across the blood brain barrier. RSC Advances. 2016; 6 (88), 85261-85274.
• Baishya R, Nayak D, Karmakar S, Chattopadhyay S, Sachdeva S, Sarkar B, Ganguly S, Debnath M. Synthesis and Evaluation of Technetium-99m LabeledBioreductivePharmacophores Conjugated with Amino Acids and Peptides for Tumor Imaging. ChemBiol Drug Des. 2015; 85: 504–517.
• Baishya R, Nayak DK, Chatterjee N, Halder KK, Karmakar S, Debnath MC. Synthesis, characterization, and biological evaluation of 99mTc(CO)3 -labeled peptides for potential use as tumor targeted radiopharmaceuticals. ChemBiol Drug Des. 2014 Jan;83(1):58-70.
• PranabJyoti Das , Paramita Paul , Biswajit Mukherjee , BhaskarMazumder , LaboniMondal , Rinku Baishya , Mita Chatterjee Debnath , and Kumar SauravDey. Pulmonary Delivery of Voriconazole Loaded Nanoparticles Providing A Prolonged Drug Level in Lungs- A Promise For Treating Fungal Infection. ACS Mol. Pharmaceutics 2015, 12 (8), pp 2651–2664.
• Nayak DK, Baishya R, Natarajan R, SenT,Debnath MC. Tricarbonyl 99mTc(I) and Re(I)–thiosemicarbazone complexes: synthesis, characterization and biological evaluation for targeting bacterial infection. Dalton Trans., 2015,44, 16136-16148.
• Nayak DK, Halder KK, Baishya R, Sen T, Mitra P, Debnath MC. Tricarbonyltechnetium(I) and tricarbonylrhenium(I) complexes of amino acids: crystal and molecular structure of a novel cyclic dimeric Re(CO)3-amino acid complex comprised of the OON donor atom set of the tridentate ligand. Dalton Trans.2013 Oct 7;42(37):13565-75.
• Nayak DK, Baishya R, Halder KK, Sen T, Sarkar BR, Ganguly S, Das MK, Debnath MC. Evaluation of 99mTc(i)-tricarbonyl complexes of fluoroquinolones for targeting bacterial infection. Metallomics.2012 Nov;4(11):1197-208.

• National Merit Scholarship (2007-2009) GATE-2007 {Graduate Aptitude Test in Engineering} in Pharmaceutical Sciences conducted by Indian Institute of Technology, Kanpur.
• Institute Gold Medal for Overall Excellence among all the students of Master of Science (Pharm.) who graduated in 2009 from National Institute of Pharmaceutical Education and Research, Kolkata (an Institute of National Importance).
• Silver Medal for merit among all the students of Bachelor of Pharmacy (B. Pharma.) who graduated in 2007 from Dibrugarh University, Dibrugarh.
• DAE-Senior Research Fellowship at CSIR-Indian Institute of Chemical Biology, Kolkata from May 2010 to April 2013.
• CSIR-Senior Research Fellowship at CSIR-Indian Institute of Chemical Biology, Kolkata from June 2013 to July 2014.
• The PBC Fellowship Program for Outstanding Post-Doctoral Researchers from China and India 2015-16 for 3 years in Clinical Biochemistry and Pharmacology Department, Ben Gurion University, Israel.